ABSTRACT
The 29th European Congress on Obesity(ECO) was held in Maastricht, Netherlands from May 4 to May 7, 2022. The conference consisted of five sections with a great amount of information: basic science, behavioural and public health, childhood and adolescent obesity, management and intervention, and metabolic surgery, with a total of more than 80 special reports. We summarized the epidemiological investigation, diagnosis, complications and management of obesity, aiming to provide reference information for the comprehensive management of obesity in China.
ABSTRACT
Lectin-likeoxidizedLDLreceptor-1(LOX-1)isoneofthemajorreceptorsoftheoxidized low-density lipoproteins (oxLDL). Recent research suggests that LOX-1 can not only bind, neutralize and degrade oxLDL, but also bind some non-oxidized lipoproteins and apoptotic blood cel s. LOX-1 is involved in the process of atherosclerosis through a variety of w ays, such as activating platelet, inducing inflammatory reaction, promoting the proliferation and migration of vascular smooth muscle cels. This article reviews the related research progress from the relationship betw een the structure and function of the LOX-1 and its lipid metabolism and the pathogenesis of atherosclerosis.